Role of Cytokines in Schizophrenia

Role of Cytokines in Schizophrenia Introduction: Schizophrenia is a mental disorder. Over 1% of the world population is affected by this mental disorder (Bakhshi Chance, 2015). A cytokine hypothesis has been proposed, which elucidates the role of cytokines in this disease. Cytokines such as IL-6, TNF-ÃŽÂ ±, sIL-2R, and IL-1RA were found to be over-expressed by the peripheral blood mononuclear cells (Potvin et al., 2008; Goldsmith et al., 2016), in which interleukin-6 is considered to be the key player in schizophrenia. IL-6 has glycoprotein gp130 as a common membrane receptor and as a signal transducer, which can have both anti-inflammatory and pro-inflammatory effects (Scheller et al., 2011). The anti-inflammatory effects of interleukins present in the blood serum of patients with schizophrenia must be understood. Upcoming therapeutic research focuses on astrocytes due to their expression of class II MHC antigens and the production of pro and anti-inflammatory cytokines. The hypothesized outcome is that IL-6 also induces anti- inflammatory effects which help the astrocytes to maintain the homeostasis. This will enable the researchers to explore further the pathophysiology of schizophrenia based on the cytokine hypothesis. The effects of IL-6 on astrocytes will open the door to a new area of research and will help in exploring the effects. The impact of the research on Healthcare: According to the data and statistics from the community studies of the European Union (EU), 27% of the adult population experienced at least one mental disorder in the past year (World Health, 1992). In Ireland, both private healthcare sector and public healthcare sector exists to assist the people of Republic of Ireland during an illness (Book, 2007). The Irish legislations Health Act 2004 governs the public health care system which is responsible for the people living in Ireland (Pearson et al., 2012). In the year 2010, à ¢Ã¢â‚¬Å¡Ã‚ ¬2,862 Euros was spent on the health of a single individual residing in Ireland of which 79% was provided by the Irish government (Pearson et al., 2012). Looking the statistics, it is summarized that nearly seven people out of 100 spend the money for treating schizophrenia that would be approximately à ¢Ã¢â‚¬Å¡Ã‚ ¬20,900 Euros. Biomarkers are biological markers such as viral proteins, cytokine, hormones, etc. which can be used as a measurable indicato r of the biological state or condition (OConnell et al., 2014).   The main challenges in the biomarkers identification of schizophrenia are the unknown pathophysiology. However, biomarkers such as cytokines are considered due to the development of new hypotheses such as the cytokine hypothesis (Mansur et al., 2012). Understanding the roles of IL-6 in schizophrenia, can be used as a biomarker for the initial clinical diagnosis of schizophrenia patients, and to help create individualized treatment plans. The timescale for a product launch: If the research is proven successful, IL-6 based biomarker assays and treatments will be developed as a product from pharmaceutical companies. The developed products such as biomarker assays for IL-6 over or under expression detection and anti-IL-6 drugs will undergo the process of ethical approval and clinical trials which include four major stages. They are pre-clinical trials, clinical trials (Phase I, II and III), ethical approval and marketing (Phase IV) which would take a period of 20 to 30 years (DiMasi et al., 2003). There are anti-IL-6 drugs already in the market for the treatment of diseases which are related to Auto-immunity and other immune-based diseases which can cross the blood-brain barrier. These drugs may take a period of 8 -15 years to is the anticipated timescale for the proposed benefits to come into the market for the utilization of the schizophrenia patients. The importance of the product: The anti-inflammatory effects of IL-6 occur due to classical signaling pathway in which IL-6 binds to the membrane-bound cell surface receptor (IL-6R). Trans-signaling pathway provides the pro-inflammatory implications of the IL-6 (Scheller et al., 2011). Blocking the Trans-signaling pathway of the IL-6 is the target for the anti-IL-6 drugs. This might hold the capabilities for the treatment of Schizophrenia. The biomarker assays for IL-6 detection may help a person to identify whether the person is susceptive to schizophrenia shortly. This can help the doctor to give personalized treatment for the person based on the medical technologies available. The importance of the IL-6 product can be understood from the article Young people have the highest rate of psychiatric admissions which was published in Irish Times on 21 July 2016. The article discussed the young people (20 to 24) who are getting admitted to psychiatric hospitals for the 2015 (Edwards, 2016). The major diseases diagnosed for the admission are schizophrenia, depression, alcoholic disorders and mania which increases day by day (Edwards, 2016). Correlation with public, governmental and business sectors Public awareness campaigns and outreach to the doctors is the primary step in spreading the importance of the IL-6 as a biomarker for schizophrenia research. The second phase would be to use the primary media tools such as newspaper and radios so that the people does not expect from the research or get panic or distressed by the research. If the product is ethically permitted and the research becomes a success a contract between a pharmaceutical company or a medical diagnostic device company for establishing the result in the society. The completed biomarker assays for IL-6 detection product would be straightforward and easy to use similar to us such as a blood sugar and cholesterol test which can be utilized by the public without the doctors supervision. Biomarker assay kinds of products are advertised in the media such as television, newspaper, the internet, etc. for the maximum dissemination of the product. In the case of anti-IL-6 drugs, a patent is claimed by the pharma company which owns the contract, and a certain amount of percentage is given as royalty to the researcher. The patent is registered in a common government body, and the prize is sometimes fixed by the government of the country which accepts the drug. Conclusion: Schizophrenia is perhaps the most daunting psychiatric disorder, characterized by its life-altering symptoms, such as hallucinations and delusions. There is currently no precise explanation of its pathophysiology. Schizophrenia is explained as the biochemical imbalance in the brain which may exist due to many factors. Upcoming therapeutic research focuses on astrocytes due to its expression of class II MHC antigens and the production of pro and anti-inflammatory cytokines. By combining the Cytokine hypothesis and Neurodevelopmental hypothesis, it is possible to understand the pathophysiology of schizophrenia and the role of astrocytes in maintaining the homeostasis and cytoarchitecture of the brain. The cytokine IL-6 has been regarded as a pro-inflammatory cytokine, but it also has many anti-inflammatory and regenerative activities. Understanding the roles of IL-6 in schizophrenia can be used for the initial clinical diagnosis of schizophrenia patients, and to help create individuali zed treatment plans. Products such as biomarker assays for IL-6 and anti-IL-6 drugs can be developed for the treatment of schizophrenia from the research. The anticipated timescale for these drugs or assays to come into the market can take a period of 8 -15 years. A decade is not a big issue for the young people who are getting admitted to psychiatric hospitals diagnosed a schizophrenic patient. This can help the doctor to give personalized treatment for the person based on the medical technologies available. References: Bakhshi, K. Chance, S.A. (2015) The neuropathology of schizophrenia: A selective review of past studies and emerging themes in brain structure and cytoarchitecture. Neuroscience, 303, 82-102. Book, I.S. (2007) Irish Statute Book. DiMasi, J.A., Hansen, R.W. Grabowski, H.G. (2003) The price of innovation: new estimates of drug development costs. Journal of health economics, 22, 151-185. Edwards, E. (2016) Young people have highest rate of psychiatric admissions. In Secondary Edwards, E. (ed) Secondary Young people have highest rate of psychiatric admissions, pp. Pages, http://www.irishtimes.com/news/health/young-people-have-highest-rate-of-psychiatric-admissions-1.2729673 (February 24, 2017). Goldsmith, D.R., Rapaport, M.H. Miller, B.J. (2016) A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression. Mol Psychiatry, 21, 1696-1709. Mansur, R.B., Zugman, A., Asevedo, E.M., da Cunha, G.R., Bressan, R.A. Brietzke, E. (2012) Cytokines in schizophrenia: possible role of anti-inflammatory medications in clinical and preclinical stages. Psychiatry Clin Neurosci, 66, 247-260. OConnell, K.E., Thakore, J. Dev, K.K. (2014) Pro-inflammatory cytokine levels are raised in female schizophrenia patients treated with clozapine. Schizophr Res, 156, 1-8. Pearson, M., Lafortune, G. Vincent, F. (2012) Health spending in Europe falls for the first time in decades. In Secondary Pearson, M., Lafortune, G. Vincent, F. (eds) Secondary Health spending in Europe falls for the first time in decades, pp. Pages, http://www.oecd.org/newsroom/healthspendingineuropefallsforthefirsttimeindecades.htm (February 24, 2017). Potvin, S., Stip, E., Sepehry, A.A., Gendron, A., Bah, R. Kouassi, E. (2008) Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biol Psychiatry, 63, 801-808. Scheller, J., Chalaris, A., Schmidt-Arras, D. Rose-John, S. (2011) The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim Biophys Acta, 1813, 878-888. World Health, O. (1992) The ICD-10 classification of mental and behavioural disorders : clinical descriptions and diagnostic guidelines. World Health Organization, Geneva.

Example of Interview Protocol

Interview Protocol: 1. How would you define biology? 2. How would you define life? 3. Give 5 examples of life and explain why they exhibit life. 4. What is the smallest unit of life? 5. Is soil alive? Why or why not? 6. Is air alive? Why or why not? 7. What body part makes us most alive? Why? Interview #1 Interviewer (LH): How would you define biology? Interviewee (BM): Um.. as a part of life LH: Okay, how would you define life? BM: Uh.. everything around you†¦from the sky to the grass LH: Can you give 5 examples of life and explain why they exhibit life.BM: Plants, because you need them to breathe oxygen, yourself, because you are you, animals, because they are part of the food chain (she flashed a thumbs up here because she was proud she recalled this information), the sun, because you need it to grow and not be moody, and water, water because everything needs water. LH: Nice.. what is the smallest unit of life? BM: Um†¦um.. um†¦I know this†¦ LH: I know you doâ € ¦ (Another minute passed and never recalled despite looking around the room and looking directly at the cell poster) LH: Is soil alive? Why or why not?BM: Yes, because you can make it grow. LH: Is air alive? Why or why not? BM: Um†¦(about 30 second delay)†¦I am going to say no†¦ LH: Why not? BM: (she shrugs) LH: Okay, go back to how you defined life. How do you define life? What makes something alive to you? BM: It grows and survives. LH: Okay, so is air alive? BM: No, because it doesn’t grow. LH: One of your examples of life was the human body. What part of the human body makes you most alive and why? BM: Your heart because it makes everything move. Because you can live without a brain, can’t you? You can be brain dead.LH: But once your heart gives out then you are dead? BM: Yes, because you still can live†¦ LH: Without a brain but not without a heart? BM: You can live more without a brain then a heart. LH: Very nice, thank you for participatin g. Interview #2: Interviewer (LH): How would you define biology? Interviewee (YC): The study of life. LH: And†¦how do you define life? YC: Something that moving, breathing, functioning LH: Ok.. can you give me five examples of life and explain why they exhibit life. YC: Plants, cause they grow, humans, cause they move around, they function, they think and they also grow.. m.. wait†¦animals cause that’s like humans†¦. um.. LH: Two more YC: I really can’t think of two more. Those are the only ones I can think of right now. LH: Ok, so plants, animals and humans, what is the smallest unit of life? YC: The cell LH: And, is soil alive to you? Why or why not? YC: Um.. yeah because it makes things grow. LH: Okay.. is air alive to you? Why or why not? YC: No, because in order to be alive you have to be, like, functioning, growing, moving and air is just two chemicals put together to make one chemical. LH: Okay, and what body part makes a human being most alive an d why?YC: The heart because without your heart you can’t function, you can’t, because your heart makes your whole body function so without that you won’t be able to function. Because the heart is the one that produces the blood and the blood sends out to all of your†¦um.. cells and all your body parts. It also sends out reflexes. It also helps with your reflexes and everything. LH: Nice, thank you. Analysis: The most surprising part of the interview came after the interview when the two subjects started arguing about their answers. I invited two friends to come after school but interviewed them separately.After I was done with the second interview, the girls started discussing how they answered each question. Their focus was specifically on the last two questions: is air alive and what part of the body makes a human being alive? They started discussing molecules and molecular interactions in air that could create life or prevent life depending on the qualit y of air. In addition, they considered the importance of the brain in the human body and discussed the implications of being brain dead but still alive. After some discussion, the girls decided the brain is the coach and the heart is the player.Both students are basketball players so it helped them to process the information by relating to basketball. In other words, the coach gives direction but the players still have to execute the plays. Another point of interest was the correlation of grades with ease and accuracy of recall. My first subject is receiving a B in my class and the second subject an A. The first subject knew the concepts but had more difficulty with the exact definition. The first subject talked around topics demonstrating knowledge of content standards but had difficulty pinpointing her ideas.The second subject gave exact definitions and answers quickly. The comfort level was visible in the answers provided, both in accuracy and timing. In addition, despite discuss ing the characteristics of life, I realized both students still created a superficial definition of life. They summarized life as something that moves and grows and breathes, but they did not consider reproduction and they are made of cells and more technical aspects of the definition of life. The students also had trouble with their own definition when I started asking them about specific questions regarding living/non-living parts.Although it was interesting the second subject had a greater connection between her definition and her explanation of why a heart is the most critical organ for life. I also noticed when giving examples of life, both subjects focused on broad categories of life: plants, animals, humans and neglected specific examples of living things. I would be interested to see if a younger student would name specific living things or focus on broad categories. I suspect the broad categories come from the fact we are studying cells and just studied ecology and the focu s is on plant versus nimal or consumer versus producer. After completing my interview I realized my questions were too narrow. I tried to predict what the students would say and create appropriate follow-up questions but the questions still had short answers. I need to reflect on how to write my questions to solicit longer responses with more detail to demonstrate feeling. The discrepancy between what I anticipated and what happened could be the result of the nature of the survey and the focus on content compared to my research survey that focuses on experiences and emotions.

Cover Sheet For Submission Of A Work For Assessment

Cover sheet for submission of work for assessment UNIT DETAILS Unit name Fundamentals of Marketing Class day/time Wednesday / 2.30pm Office use only Unit code MKT10007 Assignment no. 1 Due date Friday 19th August Name of lecturer/teacher Mr Gordon Campbell Tutor/marker’s name Ms Shamain Wickramasinghe Faculty or school date stamp STUDENT(S) Family Name(s) Given Name(s) Student ID Number(s) (1) Kushani Gunawardana 100028905 (2) (3) (4) (5) (6) DECLARATION AND STATEMENT OF AUTHORSHIP 1. I/we have not impersonated, or allowed myself/ourselves to be impersonated by any person for the purposes of this assessment. 2. This assessment is my/our original work and no part of it has been copied from any other source†¦show more content†¦Plagiarism occurs when the origin of the material used is not appropriately cited. Student signature/s I/we declare that I/we have read and understood the declaration and statement of authorship. (1) Kushani (4) (2) (5) (3) (6) ________________________________________ Further information relating to the penalties for plagiarism, which range from a formal caution to expulsion from the University is contained on the Current Students website at www.swin.edu.au/student/ Copies of this form can be downloaded from the Student Forms web page at www.swinburne.edu.au/studentforms/ PAGE 1 OF 1 1.0 Introduction to the Report This report demonstrate how Kraft cheese cheddar behave to impress consumer decisions to purchase using the Marketing Mix strategy. This report also clarify and investigate the current brand environment and the reliability of the Marketing Mix. The Marketing Mix contain four Ps and Brand position is the area that live in the customer’s mind. This report discuss the purchase at the Woolworths super market in Roxburgh Park on 8/11/2016. 2. Analysis of the Marketing Mix and the Brand Positioning 2.1 The product and the product category The Kraft cheese cheddar product is a cheese; a cheddar has more flavour and it is hard. This product go with the ‘savoury spread’ category. 2.2 The 4Ps 2.2.1

Cancer A Common Misconception About Cancer - 5956 Words

INTRODUCTION What is Cancer? A common misconception about cancer is that it is a relatively new disease. Cancer, like many diseases have been prevalent in the populations of many species, not just humans, for millennia. In fact it was a Roman doctor who translated the Greek word â€Å"carcinos† into â€Å"cancer†, a Latin word meaning â€Å"crab†. The reason why cancer is referred to as a crab is because a cancer â€Å"adheres to any part that it seizes upon in an obstinate manner like a crab† (Ramzi S. Cotran et al. Robbins- Pathologic Basis of Disease, 1999). Cancer or neoplasm is any new abnormal growth that is growing in a very fast and uncoordinated way compared to normal tissues. What we refer to as a tumour is in fact the same as a neoplasm and any non-neoplastic usage of the term tumour has passed into limbo. A neoplasm can be benign or malignant whereas cancer refers to malignant neoplasm. Cancer Today Cancer is one of the most well-known and most talked about disease in today’s world. This is because the incidence of the disease has never been higher. It is estimated that around 2.5 million people in the UK today, have been diagnosed with cancer. This figure has increased by around 500,000 in the last five years, and it is said that by the end of 2016 over a thousand people will be diagnosed with cancer every day in the UK. According to Cancer Research UK, 1 in 2 people today will be diagnosed with cancer at some point in their lifetime. The reason why the incidence of cancer hasShow MoreRelatedBreast Cancer : Education Is Vital871 Words   |  4 PagesBreast Cancer: Education is Vital Every nineteen seconds a woman is diagnosed with breast cancer in the world, yet controversy still surrounds the issue of breast cancer education and recommendations for screenings (ww5.komen.org). 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The Five Pillars Of Islam - 2378 Words

The Five Pillars Of Islam Subject: Religious Education Name: Nathaniel Hall Date of Submission: April 9, 2014 Table Of Contents Introduction†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦1 Objectives†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦2 The Shahadah†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦.3 The Salat†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..4 The Zakat†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦...5 The Sawm†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.†¦6 The Hajj†¦.............................................................................................7 Comprehension†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦8 Conclusion†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.9 Bibliography†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦10 Introduction This project is based on The Five Pillars and it aims to†¦show more content†¦The Fajr prayer is performed before sunrise, Dhuhr is performed in the midday after the sun has surpassed its highest point, Asr is the evening prayer performed before sunset, Maghrib is the evening prayer performed after sunset and Isha is the night prayer. All of these prayers are recited while facing in the direction of the Kaaba in Mecca and forms an important aspect of the Muslim Ummah. Muslims must wash before prayer; this washing is called wudu (purification). The prayer is accompanied by a series of set positions called the rakat sequence which includes the following: bowing with hands on knees, standing, prostrating and sitting in a special position (not on the heels, nor on the bottom). Prayer is obligatory for all Muslims except those who are disabled, prepubescent, very sick, lactating, pregnant, menstrual bleeding, frail and elderly or travelling on a long journey and it has been estim ated that roughly 49% of Muslims pray their daily prayers regularly. A Muslim may perform their prayer anywhere, such as in offices, universities, and fields. However, the mosque is the more preferable place for prayers because the mosque allows for fellowship. The chief purpose of Salat in Islam is to act as a person s communication with and remembrance of God. By reciting the first Surah of the Qur an, as required in all daily worship, the worshipper can stand before God, thank and praise Him, and to ask for guidance along the Straight Path.Show MoreRelatedThe Five Pillars Of Islam989 Words   |  4 Pagesimportant Muslim practices are the Five Pillars of Islam. These duties are rooted in the teachings of the Qur’an and in the example of the prophet, Muhammad. Therefore, Muslims are expected to observe them with the utmost respect and devotion. These pillars form the foundation for all good deeds and acts of worship to God. And, carrying out the Five Pillars demonstrat es that faith comes first. The profession of faith, shahadah, is the first of the Five Pillars. The shahada is the most fundamentalRead MoreFive Pillars Of Islam And Islam1119 Words   |  5 PagesFive Pillars of Islam All great things are built on a solid and strong foundation. The religion of Islam is no different. The foundation on which Islam was built is known as The Five Pillars of Islam. These are the essential duties that are required of all Muslims. The pillars are the shahadah (declaration of faith), salah (establishment of the five ritual prayers), zakah (almsgiving), sawm (fasting the month of Ramadan), and hajj (pilgrimage to the holy city of Mecca). These five pillars are inRead MoreIslam : The Five Pillars Of Islam1412 Words   |  6 Pagesto reflect and cultivate their faith through practicing the Arkan al-Islam - the Five Pillars of Islam. Islam embraces the paradigm of submission to the will of Allah for adherents to understand their place in the universe. The pillars are a foundation for the Muslim faith as evident by Muhammad s statement of ‘Islam is built upon five [pillars]’ recorded in the Hadith 3. This entails the declaration of faith (Shahadah), the five dai ly prayers (Salat), almsgiving (Zakat), fasting during the monthRead MoreThe Five Pillars Of Islam Essay764 Words   |  4 Pagesal-Bukhari, fortunately, the five pillars of Islam are actually seen outlined within the very first Hadith. The Five pillars, according to Traditions and Encounters, are a framework of obligations present to help form a unified Islamic community (p.263-264); Muhammad himself, in the 38th hadith, describes the five pillars as the baseline obligations of a Muslim to please Allah and enter paradise. The first Hadith states thusly, â€Å"Allah’s Apostle said: Islam is based on five [principles]: 1. To testifyRead MoreThe Five Pillars Of Islam1201 Words   |  5 PagesThe five pillars of Islam are five official acts considered mandatory for all Muslims. The  Quran  presents them as a structure of devotion and a sign of obligation to faith. One most accomplish them all to live a good and responsible life according to Islam. These pillars comprise o f:  Shahada which means the declaration of faith, preforming the five daily prayers, giving money to the needy and the poor, cleansing the soul through fasting during the month of Ramadan, the pilgrimage once in a lifetimeRead MoreThe Five Pillars Of Islam1591 Words   |  7 PagesIslam Notes The most important Muslim practices are the Five Pillars of Islam. The Five Pillars of Islam are the five obligations that every Muslim must satisfy in order to live a good and responsible life according to Islam. The Five Pillars consist of: Shahadah: sincerely reciting the Muslim profession of faith Salat: performing ritual prayers in the proper way five times each day Zakat: paying an alms (or charity) tax to benefit the poor and the needy Sawm: fasting during the month of RamadanRead MoreThe Five Pillars Of Islam1289 Words   |  6 Pagestrusted with something fulfill your trust, avoid sexual immorality, lower your gaze (out of modesty), and restrain your hands from injustice. One of the Five Pillars of Islam: the Pillar of faith, including belief in One God, belief in God’s scriptures, belief in God’s angels, belief in God’s messengers, and belief in the Day of Judgement. One of the five necessary purposes of Islamic law: God commands justice, doing good, and generosity towards relatives and He forbids what is shameful, blameworthyRead MoreIslam Five Pillars1344 Words   |  6 PagesExplain and analyse the significance of the Five Pillars of Islam on the individual and the community making reference to the principal beliefs where relevant. Central to the Muslim belief is the importance of devotion and total submission to Allah. This is put into practice through the Five Pillars of Islam –the five obligatory duties that must be performed by all practising Muslims. These are the acts of faith, prayer, charity, fasting and pilgrimage. Carrying out these duties creates structureRead MoreThe Five Pillars Of Islam1322 Words   |  6 Pagesof guidelines for moral instruction that is central to all. These rules are called the Five Pillars of Islam. The Five Pillars serves as a moral compass for all Muslims and are universally accepted. They are mentioned specifically in the Qur’an as they were recited to Muhammad. The first of the Five Pillars is the creed. It states that, â€Å"There is no God but Allah, and Muhammad is his messenger,†. This pillar is at the core for the Muslim faith. A person truly becomes a Muslim when he/she recitesRead MoreReligion : The Five Pillars Of Islam944 Words   |  4 PagesReligion: The Five Pillars of Islam Religion, in my words, is a term used to describe a personal set of religious attitudes, beliefs, and practices but â€Å"the groups, practices and systems that people identify as religions are so diverse that it is no easy task to bring them all under one simple definition† (Anonymous. What Is Religion? Definitions and Quotes). Religion is considered to be a very important part of life; even people who choose to not practice a religion agree that it is.   No matter

How Music Makes the World Happy Free Essays

Analysis Memory Cost In the last 30 years, the need for hard drives to be capable to hold more memory has been on a very fast rise. This Is due to our operating systems that are larger and the fact that more people needing or wanting to use computers more. Technology has grown so much. We will write a custom essay sample on How Music Makes the World Happy or any similar topic only for you Order Now 20 years ago only about half of us had computers in our homes. Today almost everybody has at least 1 desktop and 1 portable. We keep pictures of our children on computers, have more programs to use in everyday life, control our finances, do school work, our Job has a need for computers, and love to play games ND use the internet. Every day these things take up more and more memory storage. The last time researchers hit a limit for expanding memory was 2005. We take this fact, that there are limits, for granted. That every now and then there is a limit that cannot be topped. Researchers say that that limit again Is going to reached somewhere around 2013-2015. There Is a new technology for the HAD (hard disk drive) called the HAM (heat-assisted magnetic recording). This will bring massive storage growth and raise the Industry way beyond 100 TUB. Currently there is a 100 TUB hard drive. When will it be commercially available? After researching several charts I would say in about 5-10 years. At this point the average person would not even need this much memory and the price would be extremely expensive. So I am going to say in about 5-10 years we will meet supply and demand on a 100 TUB hard drive. Ten years from I am predicting that I could buy a 8 TUB hard drive for around $100 dollars. I cannot get a very educated guess on this because the all the history charts on this vary. But I took what I could buy today and used Morel’s law and came up with an 8 TUB hard drive will cost about $100 dollars In the year 2023. And that Is If we even use HAD at that time. How to cite How Music Makes the World Happy, Papers

Essay on Abortion Consider Adoption Example For Students

Essay on Abortion: Consider Adoption How would you feel if someone took away your ability to live and have a future? You wouldnt have the opportunity to crawl, take your first step, have your first kiss, or experience those butterflies in your stomach at the sight of first love. Millions of special moments, a life, shredded to pieces. This is essentially what abortion does. Abortion is not the answer in the case of an unplanned pregnancy and needs to be stopped! First of all, abortion is a type of unnecessary murder that occurs in inhumane ways and cannot be tolerated. Moreover, there are alternatives to abortion and many families who are looking to adopt. Lastly, the side effects of abortion can cause life threatening health risks to the mother. Excuses will always be made, but the bottom line is that abortion is not acceptable and should be stopped. No upstanding and sane person would ever sanction mass murder; and yet, by supporting abortion that is just what is happening. Every day 3,238 babies are killed in brutal ways inside the womb through processes such as dilation and curettage, where a loop shaped knife is used to cut the baby into pieces, then its body parts are checked in case any parts remain in the mother (Abortion). Even worse, such statistics do not include the abortions that take place due to contraceptives and the â€Å"morning after pills†. However, the most horrific aspect of this aside form sickening medical procedures and toxic medicine is the culprits. Parents, the two most important people who are supposed to protect their children, have deserted them and left them vulnerable, sentenced to death. There will always be counter arguments but all are refutable. One may ask: what about rape victims, teenage pregnancy and threats to the mothers life? They are not ready to be mothers, its not healthy, the excuses go on. They should be able to abort, right? The answer is no! Here is why: â€Å"92% of abortions in America are purely elective done on healthy women to end the lives of healthy children†. Less than 1% of abortions are done by victims of rape and 7% of abortions occur because there is a threat to the mothers life (Schwarzwalder). Therefore, abortion has gone to what some people believed to be a necessary evil to a commodity: Abortion has become mass murder of convenience. When an unplanned pregnancy occurs people, especially teens, will take the easy way out. They dont want to give up their extravagant ways of life and take responsibility for their actions. Selfishness infests their brains and all they can think of is themselves: how their lives will be ruined, they cant possibly support the child, their education will be put on hold. However, what people dont realize is everything that is material can be salvaged: they can continue their education, their family will be there to support them, the government can provide them with money. On the other hand, once a life is taken, there is no turning back. There is no restart button. Its the end. Yet, it doesnt have to be this way. If for whatever reason a mother cannot keep her child, there are many couples who yearn for opportunity to be parents, and who will be able to give a loving and stable environment to a new life. It is understandable to be overwhelmed by an unplanned pregnancy, but abortion should not be considered when alternatives like adoption exist. First of all, many people are under the misconception that adoption severs all ties of parents with their babies; however, birth parents have different adoption plans to choose from, shaped around their needs. For example, there is open adoption, where birth parents have a chance to pick the parents for their baby and have access as well as recognition as the birth parent to. Nonetheless, if keeping in contact with their child is not what the adoptive parents want, there is the option of confidential adoption, in which there would be no contact with either the adoptive family or the child (Consider Adoption). Lastly, it doesnt make anyone less of a person to admit that they cannot deal with unplanned situations, in this case pregnancy, but is it how people react to the situation that makes the difference. .ucae5b071f414d3a9a25000da79a0790b , .ucae5b071f414d3a9a25000da79a0790b .postImageUrl , .ucae5b071f414d3a9a25000da79a0790b .centered-text-area { min-height: 80px; position: relative; } .ucae5b071f414d3a9a25000da79a0790b , .ucae5b071f414d3a9a25000da79a0790b:hover , .ucae5b071f414d3a9a25000da79a0790b:visited , .ucae5b071f414d3a9a25000da79a0790b:active { border:0!important; } .ucae5b071f414d3a9a25000da79a0790b .clearfix:after { content: ""; display: table; clear: both; } .ucae5b071f414d3a9a25000da79a0790b { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ucae5b071f414d3a9a25000da79a0790b:active , .ucae5b071f414d3a9a25000da79a0790b:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ucae5b071f414d3a9a25000da79a0790b .centered-text-area { width: 100%; position: relative ; } .ucae5b071f414d3a9a25000da79a0790b .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ucae5b071f414d3a9a25000da79a0790b .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ucae5b071f414d3a9a25000da79a0790b .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ucae5b071f414d3a9a25000da79a0790b:hover .ctaButton { background-color: #34495E!important; } .ucae5b071f414d3a9a25000da79a0790b .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ucae5b071f414d3a9a25000da79a0790b .ucae5b071f414d3a9a25000da79a0790b-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ucae5b071f414d3a9a25000da79a0790b:after { content: ""; display: block; clear: both; } READ: King Louis EssayInstead of succumbing to the selfish voice in our heads that insist that a babys life will not be worth it without birth parents, people must be selfless and brave by giving the baby up. â€Å"In the USA, there are approximately two million infertile couples waiting to adopt, many times regardless of the child’s medical problems such as Down Syndrome, Spina Bifida, HIV infection or terminally ill,† (Brown). That is two million couples out there that will cherish, raise and love a baby without thought to race, disease or money. Two million couples are out there, who will be with biological parents every step of the way, and from which biologica l parent can chose who will be most appropriate for their baby. By saying no to abortion, people are giving two million couples hope. In conclusion, people should embrace adoption as an alternative to abortion, for it saves innocent lives but also the lives of the mother. Abortion eradicates babies but it can also slowly eradicate the health of the mother both physically and mentally. To illustrate, surgical, medical and chemical abortion pose serious health risks to body. Post-abortion patients are at risk of complications in future pregnancies which may include excessive bleeding, premature delivery, cervical damage, and sterility. Moreover, â€Å"Recent studies have pointed out that there is what some might term a dramatic relationship between the rate of abortion and the rising incidence of breast cancer among women who have aborted,† (Abortion). The connection is as simple as altering the natural flow of the body. Birth control pills and hormone replacement therapy increase the chances of breast cancer by exposing the body to high amounts of estrogen other than that which the body already has. Estrogen stimulates mitosis and elevated amounts of estrogen can cause errors in mitosis resulting in cancer (Lanfranchi). On the other hand, aborti on is also a hazard to a womans emotional health. To illustrate, acute grief reaction and emotional disturbances are common with abortion patients. While people realize it or not, abortion is a traumatic experience. Studies have shown that mothers who abort are at risk for suicidal thoughts, drug or alcohol abuse, and post traumatic stress disorder. (Abortion Risks: A List of Major Psychological Complications Related to Abortion). 50% of patients have emotional disturbances such as depression, insomnia, anxiety, nervousness, and grief (Abortion). In conclusion, no matter from which angle it is looked upon, abortion is not the answer and should be stopped. Firstly, it is mass murder done out of convenience and selfishness to maintain the parents lifestyle. Moreover, it is not necessary to dispose of a life when there are millions of people wanting to adopt and willing to be parents. Last, abortion is a health hazard that threatens the emotional and physical health stability of women. Abortion is a social issue that needs to be brought to awareness and stopped but the world needs your help. The world needs heroes. Anyone can be a hero, a hero requires no mask or cape, but they do require a voice. A voice that can save lives. Works Cited Abortion. American Life League.  © American Life League, Inc.. Web. 5 Nov 2013.  . Abortion Risks: A List of Major Psychological Complications Related to Abortion.After Abortion. Elliot Institute, 23 Feb. 2011. Web. 5 Nov 2013. Abortion. American Life League.  © Schwarzwalder, Rob . The Best Pro-Life Arguments for Secular Audiences.Family Research. Family Research Concil, n.d. Web. 11 Nov 2013.  . Consider Adoption. Abortion Education. N.p.. Web. 6 Nov 2013.  . Brown, Kristi. Why Do More People Choose Abortion Over Adoption?.LifeNews.com. N.p., 07 June 2012. Web. 6 Nov 2013.  . Lanfranchi, Angela. Biological Explanation.Abortion Breast Cancer. N.p.. Web. 5 Nov 2013.  .